【消炎止痛藥會降低疫苗效果？】
最近許多接種Covid-19疫苗的民眾
卡在到底...

【消炎止痛藥會降低疫苗效果？】
最近許多接種Covid-19疫苗的民眾
卡在到底要不要吃消炎止痛炎-ibuprofen
有人認為消止炎痛藥-NSAIDs💊💊💊
會降低人體對疫苗產生的免疫反應
因而降低疫苗的保護力
但疫苗的副作用讓不少民眾無法忍受
吃 or 不吃？

🔍事實上目前沒有明確的研究證實
消炎止痛藥-ibuprofen影響疫苗的保護力
況且許多公共衛生主管機關及CDC
一致建議可以適當的服用止痛/消炎止痛藥
來舒緩施打疫苗造成的不適

💉另外值得一提的是
在mRNA疫苗的人體試驗中(BNT及莫德那)
是允許民眾可以服用ibuprofen
來減輕施打引起的不適感
試驗結果疫苗防護力超過4%
間接的表示ibuprofen不會影響疫苗的保護力

================================
References
1. CDC. What to expect after getting a COVID-19 vaccine. 2020. Accessed February 17, 2021.
2. NHS UK. Coronavirus (COVID-19) vaccine. 2020. Accessed February 17, 2021.
3. Pfizer, BioNTech. A phase 1/2/3 study to evaluate the safety, tolerability, immunogenicity, and efficacy of RNA vaccine candidates against COVID-19 in healthy individuals. Study intervention PF-07302048, protocol C4591001. Updated 2020. Accessed February 17, 2021.
4. Moderna. A phase 3, randomized, stratified, observer-blind, placebo-controlled study to evaluate the efficacy, safety, and immunogenicity of mRNA-1273 SARS-CoV-2 vaccine in adults aged 18 years and older. Protocol mRNA-1273-P301, amendment 3. Updated August 20, 2020. Accessed February 17, 2021.
5. AstraZeneca. A phase III randomized, double-blind, placebo-controlled multicenter study in adults to determine the safety, efficacy, and immunogenicity of AZD1222, a non-replicating ChAdOx1 vector vaccine, for the prevention of COVID-19. Protocol D8110C00001, amendment 2. Updated September 17, 2020. Accessed February 17, 2021.
6. Janssen Vaccines & Prevention B.V. A randomized, double-blind, placebo-controlled phase 3 study to assess the efficacy and safety of Ad26.COV2.S for the prevention of SARS-CoV-2-mediated COVID-19 in adults aged 18 years and older. Protocol VAC31518COV3001; phase 3, amendment 3. Updated December 14, 2020. Accessed February 17, 2021.

---